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Blood Sugar and Brain Fitness

A recent study provides a clue into the exercise-brain fitness relation. A paper reported in the December 2008 issue of the journal Neurology shows that high levels of blood glucose (the kind that can happen in people with diabetes) may directly affect the hippocampus. Since the hippocampus is a part of the brain that is essential for memory, this study helps us understand one way in which physical fitness can affect brain function. What’s the link? We know that physical fitness improves the body’s ability to regulate blood sugar levels, so being physically fit may decrease the damage that high blood sugar levels can cause to the hippocampus.

The story is a little more complicated, though (isn’t it always)? Blood sugar is regulated by a hormone called insulin. People who have type II diabetes (the kind that people usually get later in life) have a condition called insulin resistance. This means that the body makes enough, and sometimes too much, insulin. The problem is that the insulin doesn’t have a strong enough effect. This means that the body keeps making higher levels of insulin. Exposing the body to high levels of insulin can cause problems.

In the case of the brain, insulin is very important for its function. Insulin has to cross into the brain from the blood by way of a special mechanism called a transporter protein. When insulin levels are high all the time, the body decreases the number of these transporter proteins, and the brain may not get enough insulin. Some studies have shown that insulin is important in memory function, so a decrease in the number of these transporter proteins may be yet another way that high blood sugar levels can affect memory. While all of these studies are preliminary, they add to what we know about high blood sugar, insulin resistance, and mental functioning.

There are two effective ways of keeping your blood sugar under control: diet and exercise. Following the Mediterranean diet can help, because it emphasizes the kinds of food that will help keep your blood sugar stable. Exercise has been shown to help your body be more sensitive to the effects of insulin. When your body is more sensitive to insulin’s effects, blood sugar levels will be lower and more stable. We know that following the Mediterranean diet and regular exercise can help your memory – their link to blood sugar and blood sugar’s effects on the brain may be why.

Brain Fitness

Brain Training Study Off the Ground!

computer with apple for teacher

After overcoming a number of obstacles, our study of the effects of cognitive training on fluid intelligence has finally started. We’re enrolling participants from our local Life Long Learning Program, all of whom are 50 years or older. In the study, we are comparing the effects of working memory training …

Changes in Brain Size with Aging

Picture of chimpanzee

Understanding brain aging has to be research priority. The average age of people in the US is increasing. This means that there are more older people at risk for diseases that occur as people get older, such as Alzheimer’s. In people, the size of the brain decreases as they get …

Exercise, Mitochondrial DNA, and Brain Fitness

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One very influential theory of why our physical and mental functions decline with age holds that changes in our DNA accumulate over time so that out cells don’t work any more. Perhaps the most important part of our DNA exists in every cell in a special part called the mitochondia. …

The Default Mode Network and Brain Fitness

Man sleeping on grass

If brain fitness is more than just trying to avoid memory loss as you get older (and I think it is), then understanding how you think is (I think) critical. Sometimes called metacognition, this means not just thinking, but thinking about thinking. Follow that? Metacognition is the idea that we …

Mindfulness Meditation, Brain Fitness, and Gray Matter

Buddhist monk looking out over the forest

Most people know that the brain is smaller with age, at least in part due to loss of brain cells in parts of the brain related to perception, memory, and executive processes. Anything that can slow down or reverse the process should be of interest to all of us, whatever our age. …

RSS Worry and GAD Blog

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