Home » Research » Recent Articles:

Walking, BDNF, Hippocampal Size, and Brain Fitness

Picture of people running

Maybe I have an obsession. Maybe I’m addicted to exercise. Maybe.  But here it is, once again: Yet another study has shown that aerobic exercise is good for your brain. Not only does aerobic exercise improve cognition (at least 20 or more studies have shown that), but it can help to prevent age-related declines in the size of the hippocampus. The hippocampus is a critically important structure in the brain that is a key part of a circuit that creates new memories.It tends to get smaller with increasing age, but exercise can actually increase its size. The increase in size may be related to increased levels of brain-derived neurotrophic growth factor (BDNF), a substance in the body that promotes the growth of new brain cells.

In an article published online on January 31st in the Proceedings of the National Academy of Sciences, researchers show again that regular walking can make a difference in cognition. This study is new because the researchers also looked at the volume of the hippocampus with imaging techniques and looked at BDNF levels.

Exercise and BDNF levels may also be related to the way that antidepressants work to reduce depression, and we know that for many individuals exercise improves mood. While we think of the hippocampus most often because of its role in memory, it also has important effects in regulating emotion.

You can find the abstract here. The full article is available to subscribers only.

Two More Ways to Improve Your Brain Fitness

computer with apple for teacher

One of the themes I see in much of what people write about brain fitness relates to the idea that doing something can improve how your brain works by actually changing how it works, whether it’s exercise, supplements, or computer games.

A lot of people are skeptical about this idea, perhaps because most of us are taught that the cells in our brains are pretty much fixed and don’t change over time, except for dying off as we get older.

More recent studies, though, now have shown that the brain can grow new cells. Other studies have shown that some kinds of brain training change how some of the chemicals in the brain work. And still other studies have shown that cognitive training can have long-lasting effects.

So what can you do to improve your brain fitness?

  • Find a rut and get out of it. What habit are you in, and how can you get out of it? Do you collapse on the couch every night and watch TV? Try going for a walk. Record your favorite TV show and instead spend a half hour searching the Internet for something that interests you.
  • Learn a little bit of a new language. Learning a new language may be one of the best ways to rewire your brain. Maybe you won’t learn enough to be fluent, but learning about the sounds in a new language may help your ability to pay attention to sounds, and learning new ways to express a concept may help you keep your thinking flexible. You could take a class, but more and more language resources are on the Web.

Although we still don’t know exactly how to improve brain fitness for everyone, research gives us some promising directions.

Brain Fitness

Depression and Risk for Dementia

Hispanic Woman

An article authored by a group at the University of Pittsburgh today published an article in the British Journal of Psychiatry confirming and extending our 2006 paper in the Archives of General Psychiatry showing that depression is related to an increased risk of developing dementia later in life. Our previous paper showed that having …

Strength Training and the Brain

Gray haired woman lifting weight

Lots of evidence points to the usefulness of aerobic exercise for maintaining and improving mental functioning (see a previous blog post here and an extensive review article here). It is not as clear, though, whether strength training has an effect. An article in JAMA Internal Medicine shows that even a …

Concentration

Old book pen magnifier

Maria Konnikova posts an interesting article in this past Sunday’s New York Times on the effects of undivided attention and mindfulness. In her post, she links concentration to Sherlock Holmes (perhaps because that’s a link to her forthcoming book), but she provides a nice if brief review of some of …

Cognitive Lifestyle and Neuroprotection

man thinking

A study from earlier this year sheds light on how being mentally active may confer protection for cognitive decline. Michael Valenzuela is a researcher whose work focuses on understanding the links between mental activity over someone’s entire life and their later function. In previous studies, he and his colleagues have …

Physical Activity and How Long You Live

Man riding a bicycle in a race

Lots of research has shown that, at least over short periods of time, people who are physically active are more alert, remember things better, and are in better health. But does that mean that they live longer?  A recent review article looked at this question. The authors found 13 papers …

RSS Worry and GAD Blog

  • 5 More Steps to Cope with Irritability
    This is a cross posting from my brain fitness blog. As it turns out, worry is probably bad for your brain fitness, so coping with worry not only can improve your mood but may also help improve your thinking and memory. Here the post: Irritability means letting small things that happen to all of us […]
  • Three Ways to Deal with Unconstructive Repetitive Thoughts
    Several researchers have shown that negative mood, anxiety, and distress can be associated with cognitive decline. Wilson and his colleague Patricia Boyle (both at Rush in Chicago) have shown with data from the Religious Orders Study that persons who are chronically distressed have a greater chance of cognitive decline. At the Cognitive Aging Summit (sponsor […]
  • Brain Fitness and The Mind of a Monk
    the contrast between Tibetan monks’ apparent calm, evident even on brain scans, and her own anxiety disorder. Ms. Warner says that she suffers from panic disorder, […]